How much of your chips are you prepared to give up to chase ?

I've seen some players give their whole stacks away !

To me, what you have to think of is the cost involved in chasing.  If you have an aggressive opponent, your cost will be high.  If you have a skilled opponent he will bet to protect his hand and the cost will be high.  If you have a maniac you are trying to bust, your cost will be high.  Are you getting the picture ?

If I have flopped 4 cards to a flush or straight (open ended only) draw I might consider chasing if my opponent min bets to get a feel for where he is.  I would certainly check it down should my opponent be willing but let's say my opponent bets 2x the bb.  Again, you have to not only think of calling that bet but if your card does not come do you call another bet on the turn ... and another on the river ?  What if he increases his bets on each street ?  This is where a little turns into a lot and chasing becomes not profitable at all.

Sure you will hit the odd time but the %'s favor you losing more than winning.  It's the cost of chasing that has to be taken into account.  When you stop and consider fold equity as opposed to chasing and not hitting you will come to the realization that your stack will survive longer and stay stronger with no chasing.  Your fold equity % will remain high.

When chasing you have to consider the situation at hand but also think ahead.  Then you have to ask yourself is worth it to chase ?